Conservation genomics Team Grossen at WSL

Publications

2024

Genetic load
Genetic load
Christine Grossen, Uma Ramakrishnan
Current Biology   ·   01 Dec 2024   ·   doi:10.1016/j.cub.2024.11.004
Genetic load
Genetic evidence of a hybrid swarm between Alpine ibex (<i>Capra ibex</i>) and domestic goat (<i>C. hircus</i>)
Genetic evidence of a hybrid swarm between Alpine ibex (Capra ibex) and domestic goat (C. hircus)
Alice Brambilla, Noel Zehnder, Bruno Bassano, Luca Rossi, Christine Grossen
Evolutionary Applications   ·   28 Jul 2024   ·   doi:10.1111/eva.13761
Hybridisation
A highly contiguous reference genome for the Alpine ibex (<i>Capra ibex</i>)
A highly contiguous reference genome for the Alpine ibex (Capra ibex)
F. Gözde Çilingir, Fabio Landuzzi, Alice Brambilla, Debora Charrance, Federica Furia, ..., Bruno Bassano, Stefano Gustincich, Daniel Croll, Luca Pandolfini, Christine Grossen
Cold Spring Harbor Laboratory   ·   27 Jun 2024   ·   doi:10.1101/2024.06.24.599926
Hybridisation
Facilitated introgression from domestic goat into Alpine ibex at immune loci
Facilitated introgression from domestic goat into Alpine ibex at immune loci
Xenia Münger, Mathieu Robin, Love Dalén, Christine Grossen
Molecular Ecology   ·   07 Jun 2024   ·   doi:10.1111/mec.17429
Introgression

2023

Purging and accumulation of genetic load in conservation
Purging and accumulation of genetic load in conservation
Nicolas Dussex, Hernán E. Morales, Christine Grossen, Love Dalén, Cock van Oosterhout
Trends in Ecology & Evolution   ·   01 Oct 2023   ·   doi:10.1016/j.tree.2023.05.008
Deleterious mutation load

2022

Ancient mitochondrial and modern whole genomes unravel massive genetic diversity loss during near extinction of Alpine ibex
Ancient mitochondrial and modern whole genomes unravel massive genetic diversity loss during near extinction of Alpine ibex
Mathieu Robin, Giada Ferrari, Gülfirde Akgül, Xenia Münger, Johanna von Seth, Verena J. Schuenemann, Love Dalén, Christine Grossen
Molecular Ecology   ·   05 Jun 2022   ·   doi:10.1111/mec.16503
Alpine ibex Ancient DNA
Low‐coverage reduced representation sequencing reveals subtle within‐island genetic structure in Aldabra giant tortoises
Low‐coverage reduced representation sequencing reveals subtle within‐island genetic structure in Aldabra giant tortoises
F. Gözde Çilingir, Dennis Hansen, Nancy Bunbury, Erik Postma, Richard Baxter, Lindsay Turnbull, Arpat Ozgul, Christine Grossen
Ecology and Evolution   ·   01 Mar 2022   ·   doi:10.1002/ece3.8739
Aldabra giant tortoises
Chromosome-level genome assembly for the Aldabra giant tortoise enables insights into the genetic health of a threatened population
Chromosome-level genome assembly for the Aldabra giant tortoise enables insights into the genetic health of a threatened population
F Gözde Çilingir, Luke A'Bear, Dennis Hansen, Leyla R Davis, Nancy Bunbury, Arpat Ozgul, Daniel Croll, Christine Grossen
GigaScience   ·   01 Jan 2022   ·   doi:10.1093/gigascience/giac090
Aldabra giant tortoises

2021

Design of SNP markers for Aldabra giant tortoises using low coverage ddRAD-seq
Design of SNP markers for Aldabra giant tortoises using low coverage ddRAD-seq
F. G. Çilingir, D. Hansen, A. Ozgul, C. Grossen
Conservation Genetics Resources   ·   28 Jul 2021   ·   doi:10.1007/s12686-021-01225-4
Aldabra giant tortoise
A robust sequencing assay of a thousand amplicons for the high‐throughput population monitoring of Alpine ibex immunogenetics
A robust sequencing assay of a thousand amplicons for the high‐throughput population monitoring of Alpine ibex immunogenetics
Camille Kessler, Alice Brambilla, Dominique Waldvogel, Glauco Camenisch, Iris Biebach, Deborah M. Leigh, Christine Grossen, Daniel Croll
Molecular Ecology Resources   ·   07 Jul 2021   ·   doi:10.1111/1755-0998.13452
Alpine ibex
Disentangling adaptation from drift in bottlenecked and reintroduced populations of Alpine ibex
Disentangling adaptation from drift in bottlenecked and reintroduced populations of Alpine ibex
Deborah M. Leigh, Heidi E. L. Lischer, Frédéric Guillaume, Christine Grossen, Torsten Günther
Molecular Ecology Resources   ·   24 Jun 2021   ·   doi:10.1111/1755-0998.13442
Alpine ibex

2020

Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex
Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex
Christine Grossen, Frédéric Guillaume, Lukas F. Keller, Daniel Croll
Nature Communications   ·   21 Feb 2020   ·   doi:10.1038/s41467-020-14803-1
Alpine ibex

2018

Genomic Evidence for Cryptic Speciation in Tree Frogs From the Apennine Peninsula, With Description of Hyla perrini sp. nov
Genomic Evidence for Cryptic Speciation in Tree Frogs From the Apennine Peninsula, With Description of Hyla perrini sp. nov
Christophe Dufresnes, Glib Mazepa, Nicolas Rodrigues, Alan Brelsford, Spartak N. Litvinchuk, ..., Tiziano Maddalena, Matthias Stöck, Sylvain Dubey, Daniele Canestrelli, Daniel L. Jeffries
Frontiers in Ecology and Evolution   ·   02 Oct 2018   ·   doi:10.3389/fevo.2018.00144
A comparison of genomic islands of differentiation across three young avian species pairs
A comparison of genomic islands of differentiation across three young avian species pairs
Darren E. Irwin, Borja Milá, David P. L. Toews, Alan Brelsford, Haley L. Kenyon, Alison N. Porter, Christine Grossen, Kira E. Delmore, Miguel Alcaide, Jessica H. Irwin
Molecular Ecology   ·   01 Oct 2018   ·   doi:10.1111/mec.14858
Batch effects in a multiyear sequencing study: False biological trends due to changes in read lengths
Batch effects in a multiyear sequencing study: False biological trends due to changes in read lengths
D. M. Leigh, H. E. L. Lischer, C. Grossen, L. F. Keller
Molecular Ecology Resources   ·   16 Apr 2018   ·   doi:10.1111/1755-0998.12779
Alpine ibex

2017

Heterozygosity–fitness correlation at the major histocompatibility complex despite low variation in Alpine ibex (<i>Capra ibex</i>)
Heterozygosity–fitness correlation at the major histocompatibility complex despite low variation in Alpine ibex (Capra ibex)
Alice Brambilla, Lukas Keller, Bruno Bassano, Christine Grossen
Evolutionary Applications   ·   04 Dec 2017   ·   doi:10.1111/eva.12575
Alpine ibex
Population genomics analyses of European ibex species show lower diversity and higher inbreeding in reintroduced populations
Population genomics analyses of European ibex species show lower diversity and higher inbreeding in reintroduced populations
Christine Grossen, Iris Biebach, Samer Angelone‐Alasaad, Lukas F. Keller, Daniel Croll
Evolutionary Applications   ·   27 Oct 2017   ·   doi:10.1111/eva.12490
Alpine ibex

2016

Genomic variation across the Yellow-rumped Warbler species complex
Genomic variation across the Yellow-rumped Warbler species complex
David P. L. Toews, Alan Brelsford, Christine Grossen, Borja Milá, Darren E. Irwin
The Auk   ·   01 Oct 2016   ·   doi:10.1642/AUK-16-61.1
Strong reproductive isolation and narrow genomic tracts of differentiation among three woodpecker species in secondary contact
Strong reproductive isolation and narrow genomic tracts of differentiation among three woodpecker species in secondary contact
Christine Grossen, Sampath S. Seneviratne, Daniel Croll, Darren E. Irwin
Molecular Ecology   ·   26 Aug 2016   ·   doi:10.1111/mec.13751
Microsatellite diversity of the Nordic type of goats in relation to breed conservation: how relevant is pure ancestry?
Microsatellite diversity of the Nordic type of goats in relation to breed conservation: how relevant is pure ancestry?
J.A. Lenstra, J. Tigchelaar, I. Biebach, J.H. Hallsson, J. Kantanen, ..., M. Vos‐Loohuis, M. van Straten, E.A. de Poel, J. Windig, K. Oldenbroek
Journal of Animal Breeding and Genetics   ·   24 Jun 2016   ·   doi:10.1111/jbg.12226

2014

Introgression from Domestic Goat Generated Variation at the Major Histocompatibility Complex of Alpine Ibex
Introgression from Domestic Goat Generated Variation at the Major Histocompatibility Complex of Alpine Ibex
Christine Grossen, Lukas Keller, Iris Biebach, Daniel Croll
PLoS Genetics   ·   19 Jun 2014   ·   doi:10.1371/journal.pgen.1004438
Alpine ibex

2013

Development of <scp>SNP</scp> markers identifying European wildcats, domestic cats, and their admixed progeny
Development of SNP markers identifying European wildcats, domestic cats, and their admixed progeny
B. Nussberger, M. P. Greminger, C. Grossen, L. F. Keller, P. Wandeler
Molecular Ecology Resources   ·   11 Feb 2013   ·   doi:10.1111/1755-0998.12075
European wildcat

2012

The Balanced Lethal System of Crested Newts: A Ghost of Sex Chromosomes Past?
The Balanced Lethal System of Crested Newts: A Ghost of Sex Chromosomes Past?
Christine Grossen, Samuel Neuenschwander, Nicolas Perrin
The American Naturalist   ·   01 Dec 2012   ·   doi:10.1086/668076
Sex determination systems
SEX-CHROMOSOME TURNOVERS INDUCED BY DELETERIOUS MUTATION LOAD
SEX-CHROMOSOME TURNOVERS INDUCED BY DELETERIOUS MUTATION LOAD
Olivier Blaser, Christine Grossen, Samuel Neuenschwander, Nicolas Perrin
Evolution   ·   11 Oct 2012   ·   doi:10.1111/j.1558-5646.2012.01810.x
Sex determination systems
THE EVOLUTION OF XY RECOMBINATION: SEXUALLY ANTAGONISTIC SELECTION VERSUS DELETERIOUS MUTATION LOAD
THE EVOLUTION OF XY RECOMBINATION: SEXUALLY ANTAGONISTIC SELECTION VERSUS DELETERIOUS MUTATION LOAD
Christine Grossen, Samuel Neuenschwander, Nicolas Perrin
Evolution   ·   05 May 2012   ·   doi:10.1111/j.1558-5646.2012.01661.x
Sex determination systems

2011

Microsatellite-based genotyping of MHC class II DRB1 gene in Iberian and Alpine ibex
Microsatellite-based genotyping of MHC class II DRB1 gene in Iberian and Alpine ibex
Samer Alasaad, Iris Biebach, Christine Grossen, Ramón C. Soriguer, Jesús M. Pérez, Lukas F. Keller
European Journal of Wildlife Research   ·   11 Nov 2011   ·   doi:10.1007/s10344-011-0592-0
Alpine ibex
Ever-Young Sex Chromosomes in European Tree Frogs
Ever-Young Sex Chromosomes in European Tree Frogs
Matthias Stöck, Agnès Horn, Christine Grossen, Dorothea Lindtke, Roberto Sermier, ..., Emilien Luquet, Tiziano Maddalena, Helena Clavero Sousa, Iñigo Martinez-Solano, Nicolas Perrin
PLoS Biology   ·   17 May 2011   ·   doi:10.1371/journal.pbio.1001062
Sex determination systems

2010

Effects of different mating scenarios on embryo viability in brown trout
Effects of different mating scenarios on embryo viability in brown trout
ALAIN JACOB, GUILLAUME EVANNO, BEAT A. VON SIEBENTHAL, CHRISTINE GROSSEN, CLAUS WEDEKIND
Molecular Ecology   ·   29 Oct 2010   ·   doi:10.1111/j.1365-294X.2010.04884.x
TEMPERATURE-DEPENDENT TURNOVERS IN SEX-DETERMINATION MECHANISMS: A QUANTITATIVE MODEL
TEMPERATURE-DEPENDENT TURNOVERS IN SEX-DETERMINATION MECHANISMS: A QUANTITATIVE MODEL
Christine Grossen, Samuel Neuenschwander, Nicolas Perrin
Evolution   ·   24 Sep 2010   ·   doi:10.1111/j.1558-5646.2010.01098.x
Sex determination systems